{"id":1915,"date":"2018-06-27T10:07:34","date_gmt":"2018-06-27T10:07:34","guid":{"rendered":"https:\/\/healthrights.mk\/?p=1915"},"modified":"2022-01-03T10:07:53","modified_gmt":"2022-01-03T10:07:53","slug":"who-study-shows-drug-could-save-thousands-of-women-s-lives","status":"publish","type":"post","link":"https:\/\/healthrights.mk\/?p=1915","title":{"rendered":"WHO study shows drug could save thousands of women\u2019s lives"},"content":{"rendered":"

\u0418\u0437\u0432\u043e\u0440: \u0421\u0432\u0435\u0442\u0441\u043a\u0430 \u0437\u0434\u0440\u0430\u0432\u0441\u0442\u0432\u0435\u043d\u0430 \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u0430\u0446\u0438\u0458\u0430<\/strong> – <\/strong>27.06.2018<\/strong><\/em><\/p>\n

News Release – Geneva<\/strong><\/p>\n

Audio file<\/a><\/p>\n

A new formulation of a drug to prevent excessive bleeding following childbirth could\u00a0save thousands of women\u2019s lives in low- and lower-middle-income countries,\u00a0according to a study led by WHO in collaboration\u00a0with MSD for Mothers and Ferring Pharmaceuticals.<\/p>\n

Currently, WHO recommends oxytocin as the first-choice drug for preventing\u00a0excessive bleeding after childbirth. Oxytocin, however, must be stored and\u00a0transported at 2\u20138 degrees Celsius, which is hard to do, in many countries, depriving\u00a0many women of access to this lifesaving drug. When they can obtain it, the drug may\u00a0be less effective because of heat exposure.<\/p>\n

The study, published today in the New England Journal of Medicine, has shown an\u00a0alternative drug \u2013 heat-stable carbetocin \u2013 to be as safe and effective as oxytocin in\u00a0preventing postpartum haemorrhage. This new formulation of carbetocin does not\u00a0require refrigeration and retains its efficacy for at least 3 years stored at 30 degrees celsius and 75% relative humidity.<\/p>\n

View study<\/a><\/p>\n

\u201cThis is a truly encouraging new development that can revolutionize our ability to keep mothers and babies alive,\u201d says Dr Tedros Adhanom Ghebreyesus, Director-General of WHO.<\/p>\n

Approximately 70 000 women die every year because of post-partum haemorrhage \u2013 increasing the risk that their babies also die within one month.<\/p>\n

The clinical trial, the largest of its kind, studied close to 30 000 women who gave birth vaginally in 10 countries: Argentina, Egypt, India, Kenya, Nigeria, Singapore, South Africa, Thailand, Uganda and the United Kingdom.<\/p>\n

Each woman was randomly given a single injection of either heat-stable carbetocin or oxytocin immediately following the birth of her baby. The study found that both drugs were equally effective at preventing excessive bleeding after birth.<\/p>\n

Since both drugs in the study were kept in at the temperatures required to ensure maximum efficacy of oxytocin, the trial may underestimate the benefit expected with heat-stable carbetocin use in real-life settings where oxytocin may have degraded due to exposure to higher temperatures.<\/p>\n

\u201cThe development of a drug to prevent postpartum haemorrhage that continues to remain effective in hot and humid conditions is very good news for the millions of women who give birth in parts of the world without access to reliable refrigeration,\u201d says Dr Metin G\u00fclmezoglu, from the Department of Reproductive Health and Research at WHO.<\/p>\n

The next step is regulatory review and approval by countries.<\/p>\n

WHO will ask its Guideline Development Group to consider whether heat-stable carbetocin should be a recommended drug for the prevention of postpartum haemorrhage.<\/p>\n

About the study<\/strong><\/p>\n

This WHO study, also referred to as the CHAMPION (C<\/strong>arbetocin\u00a0HA<\/strong>eM<\/strong>orrhage\u00a0P<\/strong>reventION<\/strong>) trial, was funded by MSD for Mothers. Heat-stable carbetocin was provided by Ferring Pharmaceuticals, the product innovator and oxytocin was provided by Novartis for the study. The study was conducted under a collaborative arrangement between WHO, MSD for Mothers and Ferring Pharmaceuticals. Following the positive results from the trial, the parties will now work to advance affordable access to this lifesaving drug in countries that have a high burden of maternal deaths.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

\u0418\u0437\u0432\u043e\u0440: \u0421\u0432\u0435\u0442\u0441\u043a\u0430 \u0437\u0434\u0440\u0430\u0432\u0441\u0442\u0432\u0435\u043d\u0430 \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u0430\u0446\u0438\u0458\u0430 – 27.06.2018 News Release – Geneva Audio file A new formulation of a drug to prevent excessive bleeding following childbirth could\u00a0save thousands of women\u2019s lives in low- and lower-middle-income countries,\u00a0according to a study led by WHO…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"post_series":[],"class_list":["post-1915","post","type-post","status-publish","format-standard","hentry","category-vesti","entry","no-media"],"_links":{"self":[{"href":"https:\/\/healthrights.mk\/index.php?rest_route=\/wp\/v2\/posts\/1915","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/healthrights.mk\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/healthrights.mk\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/healthrights.mk\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/healthrights.mk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1915"}],"version-history":[{"count":2,"href":"https:\/\/healthrights.mk\/index.php?rest_route=\/wp\/v2\/posts\/1915\/revisions"}],"predecessor-version":[{"id":1917,"href":"https:\/\/healthrights.mk\/index.php?rest_route=\/wp\/v2\/posts\/1915\/revisions\/1917"}],"wp:attachment":[{"href":"https:\/\/healthrights.mk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1915"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/healthrights.mk\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1915"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/healthrights.mk\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1915"},{"taxonomy":"post_series","embeddable":true,"href":"https:\/\/healthrights.mk\/index.php?rest_route=%2Fwp%2Fv2%2Fpost_series&post=1915"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}